$500 million universal flu vaccine: Moonshot-like project proposes to use 50-year old technology that likely won’t work

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Dubbed Generation Gold Standard, the project is aimed at creating a flu shot that doesn’t have to be updated every year to match the latest strains of the virus. The project also aims to produce a vaccine that could protect people against other respiratory viruses that could cause a pandemic, such as bird flu and coronaviruses.

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[T]he project plans to use an approach that would involve injecting people with a whole flu virus that has been killed with a chemical to render it harmless but is still capable of stimulating the immune system. Most vaccine experts consider the whole killed virus approach to be antiquated.

“We’re going back to technology that was used 40, 50 years ago or more. …  It’s a very old technology,” says [Dr. Gregory Poland, a vaccine expert who leads the Atria Academy of Science and Medicine in New York.] “This is what influenza vaccines in the 40s, 50s and 60s looked like.”

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