‘Deleting’ disease? How gene editing and transgenic GMO technology can cut disorders before they are inherited

‘Deleting’ disease? How gene editing and transgenic GMO technology can cut disorders before they are inherited

Elizabeth Rayne | 
What has now been proven possible was once the stuff of science fiction dreams. CRISPR has shown it can successfully ...
Disease free future? Debating the prospects of human embryo gene editing

Disease free future? Debating the prospects of human embryo gene editing

Chinese scientist He Jiankui announced that he had produced the first gene-edited human babies on November 27, 2018, shocking an ...
CRISPR’s biggest challenge is addressing complex hereditary ailments like cystic fibrosis — but progress is being made

CRISPR’s biggest challenge is addressing complex hereditary ailments like cystic fibrosis — but progress is being made

Bill Alpert | 
Treatments based on the Nobel-prize winning Crispr gene-editing approach can make permanent changes to a genetic flaw— but those edits ...
CRISPR gene-editing techniques could prevent illness by reprogramming gut bacteria

CRISPR gene-editing techniques could prevent illness by reprogramming gut bacteria

Robert Sanders | 
To date, CRISPR enzymes have been used to edit the genomes of one type of cell at a time: They ...
CRISPR gene therapy shows great promise — but evidence suggests caution about unintended consequences is warranted

CRISPR gene therapy shows great promise — but evidence suggests caution about unintended consequences is warranted

Gemma Wilson | 
CRISPR-Cas9 works by creating double-stranded DNA breaks at specific points in a DNA sequence, allowing scientists to target and edit ...
3 years ago, CRISPR was used to alter the genes of two babies in China. How are they faring now?

3 years ago, CRISPR was used to alter the genes of two babies in China. How are they faring now?

Vivien Marx | 
Three years after the ‘CRISPR babies’ burst into the public eye and caused outrage, their fate remains shrouded in secrecy ...
Regrowing limbs using CRISPR? It’s been done with lizards, with hopes that human limb regeneration will be possible in the future

Regrowing limbs using CRISPR? It’s been done with lizards, with hopes that human limb regeneration will be possible in the future

Ricki Lewis | 
I’ve admired the cockroach’s ability to regrow lost legs since learning about them while working on my PhD in developmental ...
How epigenetic tweaks can increase corn and soybean yields

How epigenetic tweaks can increase corn and soybean yields

Laurie Bedford | 
Through a field of science called epigenetics, [Sound Agriculture's On-Demand Breeding] platform increases or reduces expression of existing genes in ...
Programming biology: How gene synthesis will lead to a host of medical and drug innovations

Programming biology: How gene synthesis will lead to a host of medical and drug innovations

Yiren Lu | 
As a customer, you can visit the Twist website, upload a spreadsheet with the DNA sequence that you want, select ...
How soon will we be able to breed allergy-free cats?

How soon will we be able to breed allergy-free cats?

Temma Ehrenfeld | 
Amy Bitterman, who teaches at Rutgers Law School in Newark, gets enormous pleasure from her three mixed-breed rescue cats, Spike, ...
Could CRISPR gene editing be a solution to antibiotic-resistant superbugs?

Could CRISPR gene editing be a solution to antibiotic-resistant superbugs?

Esteban Pardo | 
The fast rise in antibiotic resistance is one of the world's most concerning health issues. Antibiotic-resistant infections kill about 700,000 ...
CRISPR poised to move from the research laboratory to direct patient care

CRISPR poised to move from the research laboratory to direct patient care

Aparna Nathan | 
Preliminary results from an ongoing trial by Intellia Therapeutics show that a CRISPR-Cas9-based drug can be delivered into the body ...
How early failures dogged gene therapy — and why the future looks so much brighter now

How early failures dogged gene therapy — and why the future looks so much brighter now

Tanya Lewis | 
Jesse Gelsinger was 18 years old in 1999, when he joined one of the first clinical trials of gene therapy ...
Gene therapy evolves to treat blood cancers and numerous other rare disorders

Gene therapy evolves to treat blood cancers and numerous other rare disorders

Lauren Gravitz | 
Gene therapy has come a long way since its first human proof-of-concept trials in the 1990s. The approach—which involves fixing ...
Video: What are the benefits — and potential threats — of the CRISPR gene editing revolution?

Video: What are the benefits — and potential threats — of the CRISPR gene editing revolution?

Walter Isaacson | 
The idea of gene editing was once a thing of the future — but today, it soon could be saving ...
One-and-done intravenous gene editing infusion might eventually be able to cure HIV

One-and-done intravenous gene editing infusion might eventually be able to cure HIV

Marie McCullough | 
In 2014, Temple University researchers proved they could use state-of-the-art molecular scissors to cut out dormant HIV hiding in human ...
Treating manic depression and mental illness is the ‘final frontier’ of CRISPR gene therapy

Treating manic depression and mental illness is the ‘final frontier’ of CRISPR gene therapy

Tana Wojczuk | 
Since the 1980s, scientists have been searching for the genetic root of manic-depression, to better understand it and treat it, ...
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Breakthrough Indian gene editing experiment restores vision to legally blind people

Bharat Sharma | 
In a groundbreaking scientific victory, scientists were recently able to restore vision in legally blind patients through a gene-editing experiment ...
Life is a genetic lottery — but that’s a far cry from saying our traits are determined or fixed

Life is a genetic lottery — but that’s a far cry from saying our traits are determined or fixed

Zulfikar Abbany | 
People are often uncomfortable or anxious about genetics. "They think genetics means our outcomes are determined and that it doesn't ...
‘They squint, they stammer, they shuffle and shamble, they flounder like seals out of water’: Demonized for being different, left-handers are DNA puzzles

‘They squint, they stammer, they shuffle and shamble, they flounder like seals out of water’: Demonized for being different, left-handers are DNA puzzles

Jonathan Jarry | 
Being left-handed can be devilishly hard. In 1937, an educational psychologist whose work was later discredited wrote of many left-handers ...
mRNA COVID vaccines were decades in the making

mRNA COVID vaccines were decades in the making

Elie Dolgin | 
In the 1990s and for most of the 2000s, nearly every vaccine company that considered working on mRNA opted to ...
In early organoid studies, CRISPR gene editing shows promise for curing cystic fibrosis

In early organoid studies, CRISPR gene editing shows promise for curing cystic fibrosis

Charlotte Douglas | 
For the first time, a type of CRISPR/Cas9 genome editing, called prime editing, has been performed in “mini-organs” to correct the ...
India and other developing countries struggling to develop regulations that match the fast-paced science of gene editing

India and other developing countries struggling to develop regulations that match the fast-paced science of gene editing

Karishma Mehrotra | 
Called CRISPR, or “clustered regularly interspaced short palindromic repeats”, the technology is a powerful tool for editing genomes. It allows ...
CRISPR gene editing to cure HIV? It’s now in clinical trials

CRISPR gene editing to cure HIV? It’s now in clinical trials

Kezia Parkins | 
The US Food and Drug Administration (FDA) has given the nod for Excision BioTherapeutics to begin trials testing CRISPR gene ...
‘Junk DNA’: The 98% of the human genome that does not encode proteins is often called useless — but the reality is more complicated

‘Junk DNA’: The 98% of the human genome that does not encode proteins is often called useless — but the reality is more complicated

Jake Buehler | 
The human genome has three billion base pairs in its DNA, but only about 2% of them encode proteins. The ...
DNA in space: First CRISPR gene-editing study by astronauts opens door to future experimentation

DNA in space: First CRISPR gene-editing study by astronauts opens door to future experimentation

Ailsa Harvey | 
The first CRISPR experiment to take place in space shows that DNA can repair itself in microgravity.  As part of ...
CRISPR opens the door to altering nature. What could go right — and wrong?

CRISPR opens the door to altering nature. What could go right — and wrong?

Hayley Bennett | 
Gene editing today usually means making precise changes using CRISPR, a bacterial DNA-cutting system adopted by scientists. It works within ...
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