Human Gene Editing
Genomic Cold War? More nations joining the US in using biotechnology to enhance military capabilities
The UK government recently announced an £800 million, taxpayer-funded Advanced Research and Invention Agency (Aria). The brainchild of the British ...
Dangerously high cholesterol? CRISPR gene editing could lower it, tests on monkeys suggest
A team of researchers from Verve Therapeutics and the Perelman School of Medicine at the University of Pennsylvania has developed ...
‘It would be huge to see my granddaughter’: In an attempt to cure blindness, scientists use CRISPR to edit DNA inside patients’ bodies
Carlene Knight would love to do things that most people take for granted, such as read books, drive a car, ...
‘Less water, fertilizer, pesticides and land’? How next-generation soy and corn seeds optimized with CRISPR and AI can increase crop yields while lowering our carbon footprint
Inari wants to engineer crops that require less water, fertilizer, pesticides and land. The company is focusing on soybeans and ...
The COVID pandemic has changed the future of CRISPR and synthetic biology, says Rahul Dhanda, Sherlock Biosciences CEO
It’s been a transformative year for synthetic biology and for the world. The COVID-19 pandemic exposed weaknesses in our global ...
‘Optogenetics’ miracle? Gene therapy and high-tech goggles partially restore sight to man blinded for 40 years
[A new gene therapy to treat blindness] relies on something called optogenetics. The idea is to edit nerve cells collected ...
Is science finally getting gene therapy right in the effort to fight intractable diseases?
Over time, researchers have devised a number of ways to manipulate the genetic activity within cells, often by giving them ...
‘Genetic pain’: Prince Harry’s comments stir controversial debate over whether we can inherit our parents’ traumas
The Duke of Sussex said he had left the UK because he wanted to “break that cycle” of “genetic pain” ...
Biofuels, bioplastics and bioremediation: How CRISPR-designed technologies can protect the environment
Nowadays, scientists can use CRISPR design technologies to protect the environment. Remember, the environment is at the mercy of human ...
Viewpoint: Slew of new books ‘accept the baseless premise propounded by many CRISPR researchers that gene modification of embryos can be done safely’, claims cell biologist
In a recent review in the New York Review of Books of four books on the prospects of using CRISPR ...
Over the next decade, CRISPR and other forms of gene editing could help people with rare disorders — and millions more with heart disease, diabetes, and chronic pain
In the next decade, Crispr-Cas9 and other new gene-editing techniques may protect the health [of] millions of people with a ...
Is embryo gene editing a technology we can afford — ethically and morally? Hank Greely address the future in ‘CRISPR People’
The following is an excerpt from Hank Greely’s book CRISPR People. I see no inherent or unmanageable ethical barriers to ...
‘Wild West of CRISPR’? Ukraine clinic promises to gene edit graying hair, skin quality and breast size
If I had to pick one country that might be the epitome of the ‘Wild West’ of reproductive and genetic ...
Video: Viewpoint — The upside is immense but ‘threats from CRISPR gene editing are too big to ignore’
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary technology that gives scientists the ability to alter DNA. On ...
The age of genetically-enhanced children is approaching. Novelist Kazuo Ishiguro imagines a have-and-have not future, and it’s not pleasant
Biotech interventions to help sick children—like gene therapy—are approached with supreme caution. If a treatment has a reasonable chance of ...
Infographic: Gene therapy drugs that silence the effects of faulty genes could help tackle Huntington’s and other neurodegenerative diseases
Huntington’s disease (HD) is an inherited condition that causes widespread deterioration in the brain and disrupts thinking, behaviour, emotion and ...
400,000 people – that’s how many die from malaria each year. Here’s how gene editing and gene drives could prevent those deaths
The estimated number of malaria deaths stood at 409,000 in 2019. There is an urgent need to find new ways ...
CRISPR can alter an embryo’s genes forever. What happens when there are ‘mistakes’?
[He Jiankui] made the first genetically modified babies in the history of humankind. After 3.7 billion years of continuous, undisturbed ...
Podcast: Ezra Klein and Walter Isaacson discuss how CRISPR is poised to redirect the future course of evolution
When future generations look back on this moment in history, will they remember the daily political fights — or will ...
How does CRISPR’s ‘on-off switch’ work? How will it revolutionize genetic research and the development of therapies?
[R]esearchers have published perhaps the greatest advance since 2013 – a way to use CRISPR as an on-off switch for ...
CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences
Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to ...
A golden age of gene therapy is now in sight
To date, just two in vivo gene therapies have been approved in the United States. Both are for what [Duke ...
An ‘off button’ for pain? CRISPR could stop the opioid crisis by tackling chronic pain at the source
[In 2006, researchers found a family in Pakistan with] mutations in a gene called SCN9A. Two other families in northern ...
Here’s the skinny on the CRISPR patent saga between the Broad Institute and the CVC group
CRISPR was first reported by Jennifer Doudna and Emmanuelle Charpentier in 2012, as an outgrowth of their work on bacterial ...
CRISPR gene editing roils public discussion over ‘what it means to be disabled’
The gene-editing technology CRISPR promises enormous potential as a therapeutic for curing illnesses, including potentially devising new vaccines. But the ...
Quickly-advancing human embryo research raises prickly ethical questions
Nature published two peer-reviewed papers about generating in vitro, with slightly different methods, “blastoids” or “human blastocyst-like structures”... Notably, none ...
New hope for Duchenne muscular dystrophy (DMD) patients? CRISPR cured a mouse — and humans could be next
DMD is a fatal — and currently incurable — genetic condition that causes the body's muscles to deteriorate over time. ...
