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Fine-tuning CAR-T cancer therapy could eliminate serious side effects, study says

Damian Garde | STAT&nbsp|&nbsp
A novel approach to CAR-T cancer therapy promises to upend what has become a truism in medicine: that the treatment’s dramatic effect ...
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‘Biotech fantasy’? This startup wants to kill cancer by targeting RNA with new generation of pills

Adam Feurstein | STAT&nbsp|&nbsp
Arrakis Therapeutics is named for the desert planet in the legendary “Dune” series of science-fiction novels. It’s an apt name because ...
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Families plagued by inherited diseases push back against ban on gene-edited embryos

Sharon Begley | STAT&nbsp|&nbsp
In 2012, scientists showed that CRISPR, an ancient bacterial immune system, can edit DNA. ... Barely three years after, leaders in ...
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Viewpoint: He Jiankui’s CRISPR babies experiment was ‘even worse than I first thought’

Henry Greely | STAT&nbsp|&nbsp
When He Jiankui announced the birth of twin girls whose DNA he had modified when they were embryos using the CRISPR ...
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Making the case for lifting the US ban on 3-parent babies

Emily Mullin | STAT&nbsp|&nbsp
A Greek woman with a history of multiple in vitro fertilization failures gave birth to a healthy baby with DNA ...
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Viewpoint: Our desperate need for new antibiotics won’t be met without government incentives

Thomas Cueni | STAT&nbsp|&nbsp
As the number of infections resistant to antimicrobial drugs continues to rise around the world, and with it their huge ...
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US researcher: ‘3-parent’ embryos ready to implant if Congress lifts ban on controversial treatment

Emily Mullin | STAT&nbsp|&nbsp
Researchers at Columbia University in New York have created embryos containing genetic material from three people and are ready to ...
4-11-2019 brain opener free

Electrical brain zaps show promise at improving memory in older adults

Sharon Begley | STAT&nbsp|&nbsp
Shooting electrical current into the brain for just 25 minutes reversed the decline in working memory that comes with aging, ...
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Can your sex partner alter your microbiome, immune system?

Kate Sheridan | STAT&nbsp|&nbsp
People’s sexual partners could impact both their gut microbiome and their immune system, according to a new study from the University of ...
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Why esketamine will force doctors to rethink office visits for depressed patients

Amitha Kalaichandran | STAT&nbsp|&nbsp
The Food and Drug Administration approved esketamine (Spravato) for treatment-resistant depression to be administered under physician supervision. It’s a derivative of ...
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‘Wildly popular’ and unproven probiotics may interfere with some treatments

Meghana Keshavan | STAT&nbsp|&nbsp
Probiotics are wildly popular. After all, the microbial cocktails are available over the counter and have been shown to be ...
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5 things to consider with direct-to-consumer health products

Anne Wexler, Steven Joffe | STAT&nbsp|&nbsp
Direct-to-consumer (DTC) versions of teeth alignment kits, genetic tests, hearing aids, heart-rhythm monitors, neurostimulation devices, and mental health tools are ...
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Patients react after failure of promising Alzheimer drug trial: ‘Like the rug was pulled out from under us’

Andrew Joseph | STAT&nbsp|&nbsp
When Biogen and its partner Eisai announced that they were stopping two phase 3 trials of the Alzheimer’s treatment aducanumab because the ...
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This woman feels almost no pain. Could her genes lead to new treatment for chronic sufferers?

Jacquelyn Corley | STAT&nbsp|&nbsp
Doctors in Scotland were amazed when a 66-year-old woman underwent what is normally a very painful operation on her hand ...
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Viewpoint: Blood tests for cancer would be ‘less invasive, less expensive, less traumatic’

Grace Cordovano | STAT&nbsp|&nbsp
Eleven years ago, I was shocked to be diagnosed with advanced lymphoma. To offer an informed second opinion, an oncologist ...
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Gene therapy for beta-thalassemia blood disorder one step closer to European approval

Adam Feuerstein | STAT&nbsp|&nbsp
The first gene therapy to treat a rare blood disorder is one step closer to approval [March 29] following a ...
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Viewpoint: Precision medicine plagued by an ’embarrassing’ human reference genome

Sharon Begley | STAT&nbsp|&nbsp
The human reference genome, largely completed in 2001, has achieved near-mythic status. It is “the book of life,” the “operating ...
3-26-2019 gaining momentum on the road to accessible biosimilars

Viewpoint: We need to speed up biosimilar drug approval process

Carlos Sattler, Sheila Frame | STAT&nbsp|&nbsp
Generic versions of brand-name small-molecule drugs saved Americans more than $1 trillion between 1999 and 2010. Biosimilars now have the potential ...
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Why recent measles outbreaks may represent a ‘new normal’

Helen Branswell | STAT&nbsp|&nbsp
Back near the start of this century, before the full damage of Andrew Wakefield’s debunked study linking measles vaccine and ...
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China revives discredited ‘malarial therapy’ as cancer treatment

Jane Qiu | STAT&nbsp|&nbsp
American surgeon Henry Heimlich is best known for inventing a way to rescue choking victims, but a quarter-century ago, he was vilified ...
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‘Game-changing’ drug first ever postpartum depression medication approved by FDA

Adam Feuerstein | STAT&nbsp|&nbsp
The Food and Drug Administration on [March 19] approved brexanolone, the first drug specifically targeted to treat postpartum depression — ...
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Promising Alzheimer’s drug trial halted

Adam Feuerstein | STAT&nbsp|&nbsp
Alzheimer’s disease has beaten back another effort to tame it. Biogen and its Japanese pharma partner Eisai said [March 21] ...
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Is it OK to take sperm from the dead?

Andrew Joseph | STAT&nbsp|&nbsp
[A] New York judge earlier this month ordered a medical center to save the sperm of Peter Zhu, a 21-year-old cadet ...
3-9-2019 genetics diversity

Viewpoint: Genetic research can’t fulfill its potential without greater diversity in study populations

Joyce Tung | STAT&nbsp|&nbsp
Genetic differences exist between people of different ancestries. That means genetic studies that focus on just a handful of populations ...
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Tetanus infection offers ‘gut-wrenching’ warning about dangers of not vaccinating children

Helen Branswell | STAT&nbsp|&nbsp
A 6-year-old boy from Oregon who had never received a single vaccine got a cut on his forehead while playing ...
3-7-2019 vaccinations

Amidst measles outbreaks, ‘massive’ new study proves again that vaccines don’t cause autism

Helen Branswell | STAT&nbsp|&nbsp
A massive new study from Denmark found no association between being vaccinated against measles, mumps, and rubella and developing autism. In science ...
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US approves immunotherapy for breast cancer for first time

Sharon Begley | STAT&nbsp|&nbsp
Roche’s cancer immunotherapy Tecentriq (atezolizumab), a PD-L1 inhibitor, scored its fifth Food and Drug Administration approval on [March 8], for advanced triple-negative ...
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How ‘smart toilets’ and other technologies could help detect cancer before it’s too late

Sanjiv Gambhir | STAT&nbsp|&nbsp
I believe we should be more aggressively pursuing precision health: ways to prevent disease and, when that isn’t possible, intercept and ...
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