3-4-2019 la sci sn liquid biopsy cancer lung

Can a blood test lead to more precise treatments for lung cancer patients?

Matthew Herper | STAT&nbsp|&nbsp
Could a blood test help more lung cancer patients get drugs that are targeted to the genetic weaknesses of their ...
3-3-2019 unnamed file

‘Genetic crapshoot’: Two studies suggest clinical use of CRISPR hampered by off-target editing

Sharon Begley | STAT&nbsp|&nbsp
The version of CRISPR whose selling point has been its precision suffers, ironically, from the same shortcoming that has dogged ...
flu vaccine

Can vaccines be supercharged by CRISPR, creating ‘one-and-done’ virus protection?

Sharon Begley | STAT&nbsp|&nbsp
Vaccines are risky or ineffective in people with compromised immune systems, they don’t even exist for several viral diseases, and ...
chain of paper people

This small startup wants to change FDA clinical trials by making control groups unnecessary

Matthew Herper | STAT&nbsp|&nbsp
Could a startup founded by two guys in their 20s change the way medical researchers study patients? The Food and ...
2-28-2019 slider

US government’s BOLD initiative seeks to close the African-American Alzheimer’s gap

Karen Lincoln | STAT&nbsp|&nbsp
Alzheimer’s is a public health crisis for which Congress has thankfully put aside its differences long enough to pass the ...
2-18-2019 jim wilson mini e x

Pioneering ‘refugee’ from gene therapy’s darker days ‘kept the faith’

Damian Garde | STAT&nbsp|&nbsp
Gene therapy, now a pillar of biotechnology with the potential to cure deadly diseases, was once a cautionary tale of ...
Did China's government fund the controversial 'CRISPR babies' experiment?

Did China’s government fund the controversial ‘CRISPR babies’ experiment?

Jane Qiu | STAT&nbsp|&nbsp
Three government institutions in China, including the nation’s science ministry, may have funded the “CRISPR babies” study that led to ...
2-16-2019 hand kid cute leg finger foot pxhere com

‘Genome profiling’—not gene editing—could offer easiest path to smarter babies

Erik Parens, Paul Appelbaum, Wendy Chung | STAT&nbsp|&nbsp
For the foreseeable future, editing embryos to enhance IQ is a sci-fi fantasy. A different approach aimed at enhancing IQ ...
dt nasal spray x

Esketamine could soon be approved for depression, prompting ‘excitement and hesitation’

Megan Thielking | STAT&nbsp|&nbsp
The Food and Drug Administration is expected to decide in the coming weeks whether to approve esketamine, which would become the ...
2-11-2019 cancer at home boy

Rethinking cancer care: Home-based treatments may be right around the corner

Justin Bekelman, Nathan Handley | STAT&nbsp|&nbsp
Imagine having cancer and being told that most of your treatment will happen in your home instead of a high-tech ...
2-12-2019 fmi social during asco smarttrials header x r

Viewpoint: It’s time for a debate on precision medicine and its failed promises

Michael Joyner, Nigel Paneth | STAT&nbsp|&nbsp
Although some niche applications have been found for precision medicine, and gene therapy is now becoming a reality for a ...
2-7-2019 joshhillmancf x

Shortcomings of new cystic fibrosis treatments illustrate the complexity of some genetic diseases

Andrew Joseph | STAT&nbsp|&nbsp
Josh Hillman, a 23-year-old Harvard Law student from Alabama, has cystic fibrosis, the progressive genetic disease that causes frequent lung ...
art mental health mental illness face broken women

Researchers launch quest to understand why mental health treatments do or don’t work

Megan Thielking | STAT&nbsp|&nbsp
Successful mental health treatments can function like a conversation: The brain hears some kind of message — whether it’s from ...
2-3-2019 df b aeb d bf crispr

CRISPR-based drugs face tricky manufacturing problem

Jim Burns | STAT&nbsp|&nbsp
There are two key challenges in delivering a CRISPR-Cas9 therapy so it is effective in the body: It must be ...
gene

Viewpoint: Human gene-editing ethics should not ‘be left to scientists alone’

Nina Frahm, Tess Doezema | STAT&nbsp|&nbsp
There is one important takeaway from the controversy [about He Jiankui’s gene-edited babies] that seems to have gone overlooked in ...
2-4-2019 brain

Controversial brain preservation company Nectome seeks second, more ethical, chance

Sharon Begley | STAT&nbsp|&nbsp
Robert McIntyre would like to get a few things straight. That “waiting list” of people plunking down $10,000 to have ...
dog

Precision medicine for dogs? Silicon Valley startup wants to make it happen

Rebecca Robins | STAT&nbsp|&nbsp
When pet dogs are diagnosed with cancer, they typically get surgery, chemotherapy, or radiation — that is, of course, if ...
1-28-2019 flu shot custom bba b baacd dec ec b d a de cc s c

How your history with the flu could shape your body’s response to vaccines

Helen Branswell | STAT&nbsp|&nbsp
If you’ve ever gotten a flu shot — and then, later that season, gotten the flu — you were more ...
deem

Questions arise over US scientist’s role in CRISPR baby controversy

Jane Qiu | STAT&nbsp|&nbsp
An American scientist at Rice University was far more involved in the widely condemned “CRISPR babies” experiment than has previously ...
dnax

‘CRISPR babies’ prompt review of international gene-editing guidelines: They ‘were not clear enough’

Sharon Begley | STAT&nbsp|&nbsp
Less than two years after producing an exhaustive report on human genome editing, the U.S. National Academy of Medicine and the National ...
1-19-2019 diversity people

Improving personalized medicine may demand more diversity in clinical trials

Edward Abrahams, Jane Delgado | STAT&nbsp|&nbsp
Hispanic Americans have higher levels of diabetes and less access to health care services, yet they live on average about ...
1-21-2019 food safety shutdown ver

Viewpoint: We’re letting bureaucracy get in the way of diagnostic innovation

Rina Wolf | STAT&nbsp|&nbsp
Should we be making it easier for companies to bring new tests to market, rather than having a process that ...
ebola

International treaty could threaten genetics research on ebola, other infectious diseases

Helen Branswell | STAT&nbsp|&nbsp
There is something that is weighing heavily on the minds of some infectious diseases scientists these days. ... It’s an ...
1-15-2019 baby girl

‘Family duty’ could explain why so many Chinese couples signed up for controversial ‘CRISPR baby’ experiment

Wendy Tang | STAT&nbsp|&nbsp
Young adults in China feel a powerful cultural obligation to marry and have kids, but that life plan suddenly looks ...
facial

Algorithm identifies genetic mutations with just a photo

Kate Sheridan | STAT&nbsp|&nbsp
Some people’s faces — or even just a photo of them — hint at the genes they carry. And now, ...
mengla virus

New cousin to deadly Ebola virus discovered in bats in China

Helen Branswell | STAT&nbsp|&nbsp
The notorious filovirus family — which includes such dangerous actors as the Ebola and Marburg viruses — seems to just keep ...
He

Controversial Chinese gene-editing scientist downplays reports suggesting he could face death penalty

Sharon Begley | STAT&nbsp|&nbsp
The Chinese scientist who shocked the world in November by announcing that twin girls had been born from embryos that he had created ...
dsuviaapplicator

Do we really need a more potent, and more addictive, opioid?

Ed Silverman | STAT&nbsp|&nbsp
In the midst of a national opioid crisis, how badly do we need another formidable painkiller? This vexing question has ...
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