Afraid of glyphosate and other synthetic pesticides? You eat 10,000 times more of the natural ones made by plants

vegetables busted
In an ideal world, humans could grow enough food to feed the world without synthetic pesticides, but that is not the world we live in. Readily arable land is limited and all sorts of fauna and flora pests incessantly assault agriculture. At this time, pesticides are necessary tools to stave off our species’ starvation.

Despite pesticides’ obvious utility, humans are generally afraid of consuming these mostly unseen chemicals. That’s understandable, as various organizations have labeled them “toxins” or “carcinogens” and have even published lists of fruits and vegetables that contain the most synthetic pesticides, apparently so you can avoid eating them.

Rest assured, synthetic pesticide residues on food are safe in the minuscule amounts present – we’re talking parts per billion. What’s more, many are even less “toxic” than substances you encounter each and ever day. For example, glyphosate, the most commonly used herbicide in the U.S., is about three times less deadly than Tylenol and thirty times less deadly than caffeine.

organic produce

To showcase further how misplaced our fear of synthetic pesticides is, we can perform another, oft-ignored comparison: pitting synthetic pesticides on fruits and vegetables against the “natural” pesticides that they produce in far greater quantities themselves.

Yes, fruits and vegetables have evolved thousands of built-in pesticides, many of which aren’t so chemically dissimilar to the ones humans have created in labs. Apples, bananas, cherries, grapes, lettuce, mushrooms, and peas are just a sampling of foods that have these pesticides.

And guess what? We eat 10,000 times more of these pesticides than we do of the synthetic pesticides we’ve been conditioned to fear!

University of California-Berkeley biochemists Bruce Ames, Margie Profet, and Lois Swirsky Gold uncovered this fascinating nugget of information 29 years ago. In all, they found Americans consume an average of 1.5 grams of plant pesticides each day, which, again, absolutely dwarfs the pitiful amount of synthetic pesticides present, measured in the hundredths of milligrams.

Moreover, these natural pesticides might not be harmless. At the time of their study, Ames, Profet, and Gold noted that 52 of them had been analyzed in animal cancer tests, in which rodents are fed exorbitantly high doses of chemicals to see if they develop tumors. Slightly more than half were found to be carcinogens.

Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other ‘disruptive’ innovations. Subscribe to our newsletter.

So should we panic? Ames and his co-authors don’t think so. Rather, they say, their results question the validity of rodent carcinogenicity trials. The dose makes the poison, so feeding rodents massive doses of pesticides far beyond what any human would actually consume tells us little about whether or not those chemicals are actually safe to eat.

Here’s the overall takeaway: Synthetic pesticides, at their current levels in food, are safe to consume. How do we know? Because plants have been trying to “poison” us with vastly more of their own “carcinogenic” pesticides for thousands of years, and are still failing miserably.

Ross Pomeroy is the editor of RealClearScience. Follow him on Twitter @SteRoPo

This article originally ran at RealClearScience as Plants Make Their Own “Carcinogenic” Pesticides, and You Eat a Lot More of Them and has been republished here with permission.

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
DtAieAIkCZy-uchn-oqg
Viewpoint: In the science misinformed grifter game plan, the organic-food-is-healthier myth might be the worst.
ChatGPT-Image-Jun-15-2026-01_04_14-PM
Viewpoint: How politicized science became a political religion 
Screenshot-2026-07-06-at-11.30.08-AM
AI is making even its founders uneasy: ‘We find evidence of introspection, joy, satisfaction, fear, grief and unease.’
Picture1
The Lackland flu outbreak is fading but Hegseth’s military anti-vaccine fiasco is not
eu-farming-policy
EU bureaucrats are finally catching up to the gene editing revolution in food and agriculture
chjpdmf zs sci pbwfnzxmvd vic l zs ymdiylta l zsmtu nty otkwmtetaw hz uta a dzjyy euanbn
Technical milestone or designer baby obsession: Latest gene-editing advance reignites a familiar ethical debate
Food+as+Medicine
Viewpoint: Treat food as medicine
ChatGPT-Image-Jun-25-2026-12_23_17-PM
No, Bill Gates did not secretly engineer ticks to promote veganism
Screenshot-2026-07-02-at-10.03.56-AM
‘Trust, access, and equity’: After billions of doses worldwide, yet another review of COVID vaccine confirms its safety and effectiveness
Screenshot-2026-07-02-at-11.22.28-AM
Is Ebola a hoax created by fake humanitarians to steal African land and resources? Disinformation sweeps through the Congo. 
Screenshot-2026-06-15-at-1.50.43-PM
Viewpoint—Gutting the CDC: Survey of current and past CDC workforce accuses RFK, Jr. and Trump of destroying the agency and endangering public health
full
Misnamed ‘medical freedom’ movement stalls in Florida as Republicans fail to advance legislation ending school vaccine mandates
Screenshot-2026-06-30-at-10.43.50-AM
Viewpoint: Why are there no approved bioengineered insect-protected (Bt) apples?
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.