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Protecting against cancer: What can we learn from animals who live for centuries

There are an increasing number of genetic clues from animals that could provide hints to treating aging and age related ...
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Gene therapy that reboots body’s immune cells to fight non-Hodgkin’s lymphoma approved by FDA

The Food and Drug Administration on [October 19] approved the second in a radically new class of treatments that genetically reboot ...
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‘Synthetic lethality’ targets cancer cells by damaging vulnerable DNA

By designing small molecules that can “turn off” kinase enzymes stuck in the “on” position, they have managed to ward ...
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First gene therapy for inherited disease–combating blindness–approved by FDA panel

Gene therapy, which has had a roller-coaster history of high hopes and devastating disappointments, took an important step forward Thursday ...
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Should the European Union relax GMO clinical trial guidelines?

Four organisations representing pharmaceutical firms, biotech companies, universities, and research institutes are calling on the European commission to update, streamline ...
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CRISPR ear injections repair genetic hearing loss in mice

We all know that CRISPR is the next big thing in gene-editing treatments. But how do you get the versatile genetic scissors ...
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Edible ‘CRISPR pill’ could make harmful bacteria self-destruct

As resistance to antibiotics grows in the U.S., researchers are looking for new ways to fight germs like Clostridium difficile, a ...
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Upchuck factor: Alcoholism targeted with novel gene therapy

Researchers are exploring the use of a naturally occurring mutation that causes people to get sick after drinking alcohol. The ...
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David Gorski: Rigvir ‘virotherapy’ another unproven alternative medicine cancer therapy

[Editor's note: Dr. David Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute.] [Cancer ...
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Podcast: Exploring the consequences of gene editing’s links to ‘eugenics’

[Editor's note: Paul Knoepfler, a UC-Davis biology professor and researcher, is interviewed by Guy Raz for NPR's Ted Radio Hour.] ...
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First-ever gene-altering leukemia treatment approved by the FDA, uses patient cells to fight cancer

The Food and Drug Administration on Wednesday approved the first-ever treatment that genetically alters a patient’s own cells to fight cancer, a milestone ...
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Muscular dystrophy ‘death sentence’ targeted by gene therapy trials

[T]hree U.S. teams say they are ready to try to treat Duchenne [Muscular Dystrophy] with gene therapy. The first study ...
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‘Genome cloaking’ could protect genetic privacy in medical tests

It is now possible to scour complete human genomes for the presence of disease-associated genes without revealing any genetic information ...
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RNA editing could help slow progression of symptoms of ALS and Huntington’s

The most common gene editing technique, CRISPR-Cas9, only modifies DNA. That's helpful in most cases, but it means that you can't ...
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Three-person IVF as an infertility solution has a long way to go

The procedure is typically targeted at parents who want to avoid passing a potentially fatal mitochondrial disease to their child ...
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Could vitamin B3 supplements prevent birth defects?

An extra dose of vitamin B3 might help prevent certain kinds of complex birth defects, according to a new study ...
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Anti-aging hormone boosts cognitive abilities in mice – could humans be next?

[Klotho is] a naturally occurring hormone in the body. More than two decades ago, Japanese researchers discovered that this hormone ...
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Could gene editing have saved Charlie Gard?

The British infant died of a mitochondrial disease as news broke that US scientists had successfully edited a human embryo ...
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Why use gene editing on human embryos when other options are available?

Researchers in the U.S. and South Korea have shown that gene editing can correct a genetic disorder in an embryo. Using CRISPR-Cas9, ...
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CRISPR revolution: How scientists are turning gene-editing hype into food and medical breakthroughs

The powerful gene-editing tool is becoming ubiquitous, appearing in the media with ever increasing frequency. But it's more than just ...
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We each have 3 billion base pairs in our genome. Artificial intelligence can help us sort it out.

Genes carry the information that make you you. So it's fitting that, when sequenced and stored in a computer, your ...
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Are obesity, diabetes and other diseases treatable using gene-therapy skin grafts?

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how ...
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Pioneering gene therapy restores vision to people with rare retinal blindness

Spark Therapeutics is moving forward with its treatment for a type of inherited retinal dystrophy. In the wake of the ...
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Muscular dystrophy in dogs reversed with gene therapy–are children next?

Duchenne muscular dystrophy (DMD) is the most common and, sadly, the most severe form of the debilitating genetic disorder. Now ...
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Beneficial ‘natural’ gene mutation could be effective in treating sickle cell

Sickle cell disease (SCD) patients have a genetic defect that leads them to produce hemoglobin S, or sickle hemoglobin, instead of ...
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Gene therapy leukemia treatments approval expected by end of 2017

The approval of gene therapy for leukemia, expected in the next few months, will open the door to a radically ...
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Do your kids have ‘soccer genes’? The pseudoscience of many genetic tests

[A] growing number of scientists [are] pushing back against wild claims in the consumer genetics market, which is flush with tests promising ...
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Unwanted genes: Why can’t we just edit them out of our lives?

Gene therapy 2.0 using CRISPR to knock out harmful genes sounds is a great idea--if and when it works. But ...