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The quest to make CRISPR gene editing as easy as a smartphone app

[Biohacker Josiah Zayner] lives and works in Oakland, California, where he's converted a house into a scientific lab. Here, he ...
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New error-free DNA sequencing method could diagnose rare diseases

A virtually error-free new method of DNA sequencing could one day be used to diagnose extremely rare cancers and hereditary ...
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Gene therapy creates boy’s replacement skin from his stem cells

Doctors treated a 7-year-old boy’s devastating genetic skin disease—junctional epidermolysis bullosa—by genetically modifying his stem cells to create a new ...
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What’s the excitement over gene therapy?

Gene therapy has been in the news a lot of late as a potential cure for a variety of genetic ...
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Safer CRISPR? Cas13 version edits RNA, not DNA

CRISPR, while a major leap forward in gene editing, can still be a blunt instrument. There have been problems with ...
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Fighting malaria: Bacteria targets parasites in mosquito gut

Using a bacteria strain that colonizes the mosquito digestive tract and spreads rapidly throughout the populations, scientists have successfully inhibited ...
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Biohackers help ‘patient’ inject himself with experimental HIV treatment—live on Facebook

[Tristan] Roberts is about to inject himself with an experimental gene therapy for HIV, a DIY prototype treatment designed by ...
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Protecting against cancer: What can we learn from animals who live for centuries

There are an increasing number of genetic clues from animals that could provide hints to treating aging and age related ...
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Gene therapy that reboots body’s immune cells to fight non-Hodgkin’s lymphoma approved by FDA

The Food and Drug Administration on [October 19] approved the second in a radically new class of treatments that genetically reboot ...
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‘Synthetic lethality’ targets cancer cells by damaging vulnerable DNA

By designing small molecules that can “turn off” kinase enzymes stuck in the “on” position, they have managed to ward ...
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First gene therapy for inherited disease–combating blindness–approved by FDA panel

Gene therapy, which has had a roller-coaster history of high hopes and devastating disappointments, took an important step forward Thursday ...
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Should the European Union relax GMO clinical trial guidelines?

Four organisations representing pharmaceutical firms, biotech companies, universities, and research institutes are calling on the European commission to update, streamline ...
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CRISPR ear injections repair genetic hearing loss in mice

We all know that CRISPR is the next big thing in gene-editing treatments. But how do you get the versatile genetic scissors ...
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Edible ‘CRISPR pill’ could make harmful bacteria self-destruct

As resistance to antibiotics grows in the U.S., researchers are looking for new ways to fight germs like Clostridium difficile, a ...
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Upchuck factor: Alcoholism targeted with novel gene therapy

Researchers are exploring the use of a naturally occurring mutation that causes people to get sick after drinking alcohol. The ...
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David Gorski: Rigvir ‘virotherapy’ another unproven alternative medicine cancer therapy

[Editor's note: Dr. David Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute.] [Cancer ...
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Podcast: Exploring the consequences of gene editing’s links to ‘eugenics’

[Editor's note: Paul Knoepfler, a UC-Davis biology professor and researcher, is interviewed by Guy Raz for NPR's Ted Radio Hour.] ...
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First-ever gene-altering leukemia treatment approved by the FDA, uses patient cells to fight cancer

The Food and Drug Administration on Wednesday approved the first-ever treatment that genetically alters a patient’s own cells to fight cancer, a milestone ...
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Muscular dystrophy ‘death sentence’ targeted by gene therapy trials

[T]hree U.S. teams say they are ready to try to treat Duchenne [Muscular Dystrophy] with gene therapy. The first study ...
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‘Genome cloaking’ could protect genetic privacy in medical tests

It is now possible to scour complete human genomes for the presence of disease-associated genes without revealing any genetic information ...
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RNA editing could help slow progression of symptoms of ALS and Huntington’s

The most common gene editing technique, CRISPR-Cas9, only modifies DNA. That's helpful in most cases, but it means that you can't ...
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Three-person IVF as an infertility solution has a long way to go

The procedure is typically targeted at parents who want to avoid passing a potentially fatal mitochondrial disease to their child ...
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Could vitamin B3 supplements prevent birth defects?

An extra dose of vitamin B3 might help prevent certain kinds of complex birth defects, according to a new study ...
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Anti-aging hormone boosts cognitive abilities in mice – could humans be next?

[Klotho is] a naturally occurring hormone in the body. More than two decades ago, Japanese researchers discovered that this hormone ...
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Could gene editing have saved Charlie Gard?

The British infant died of a mitochondrial disease as news broke that US scientists had successfully edited a human embryo ...
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Why use gene editing on human embryos when other options are available?

Researchers in the U.S. and South Korea have shown that gene editing can correct a genetic disorder in an embryo. Using CRISPR-Cas9, ...
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CRISPR revolution: How scientists are turning gene-editing hype into food and medical breakthroughs

The powerful gene-editing tool is becoming ubiquitous, appearing in the media with ever increasing frequency. But it's more than just ...
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We each have 3 billion base pairs in our genome. Artificial intelligence can help us sort it out.

Genes carry the information that make you you. So it's fitting that, when sequenced and stored in a computer, your ...