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Injecting tumors with a flu shot ignites cancer-killing immune response in mice

Ashley Yeager | 
Nearly 5,000 years ago, Egyptian physician Imhotep observed a grotesque but revealing detail about tumors: some grew so large that ...
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‘A cleaner kill’: Harnessing the body’s immune system to battle cancer

Sam Moxon | 
What if your immune system could kill cancers in the same way it does colds and flu? This concept may ...
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Coronavirus immunotherapy could arrive by early summer. Is ‘record time’ fast enough?

Maggie Fox | 
Blood-plasma-based cures aren’t just the stuff of movies. There’s plenty of science to back the idea that blood products from ...
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Viewpoint: AI could guide us in understanding which cancer patients likely to benefit from expensive immunotherapy

Ofer Sharon | 
Over the last decade, significant advances in research, education, early detection methods and treatment have boosted cancer survival rates while ...
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Immunotherapy breakthrough? CRISPR-edited immune cells proven safe for use in cancer patients in early stage trial

Ed Cara | 
Now for the first time in the U.S., researchers say they’ve shown that CRISPR-edited immune cells can be safely given ...
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T-cell that can fight all cancers: Scientists discover promising part of our immune system

James Gallagher | 
Our immune system is our body's natural defence against infection, but it also attacks cancerous cells. The scientists were looking ...
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Refining CAR-T therapy could halt ‘violent, life-threatening’ immune reactions

Sharon Begley | 
CAR-T cells that have been so successful against some leukemias and lymphomas often cause a violent and even life-threatening immune ...
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Expensive CAR-T therapy raises difficult question: ‘What is the price of a human life?’

Jonathan Jarry | 
A new type of therapy for certain blood cancers is ingenious but it raises important questions about its cost, both ...
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‘Why didn’t we think of this earlier?’ Immunotherapy could treat more than just cancer

Karen Weintraub | 
Immunotherapy has transformed cancer care. Now the tools and new knowledge created by this strategy for treating disease by stimulating ...
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Promising immunotherapy drug to treat peanut allergies may be approved although 10% of study subjects had serious side effects

Ed Cara | 
On [September 13], a panel of experts assembled by the Food and Drug Administration voted that the agency should approve a drug ...
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‘It’s very encouraging’: Experimental gene therapy shows promise for glioblastoma patients in clinical trial

Ruth Williams | 
An inducible, tumor-localized gene therapy has been tested for the first time in glioblastoma patients. The two-part approach, which involves ...
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Fighting cancer by stimulating the immune system with injections directly into the tumor

Emma Yasinski | 
This past April, Mount Sinai oncologist Joshua Brody and his team announced a clinical trial that delivers immune modulators directly ...
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‘Cancer vaccine’ boosts survival rates when combined with immunotherapy drugs in small study

Sharon Begley | 
The largest study to date of a “cancer vaccine” plus one of the immunotherapy drugs that has revolutionized cancer treatment ...
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Some powerful new cancer drugs trigger diabetes for unknown reasons

Elie Dolgin | 
The first two rounds of treatment went off without a hitch. But last November, after receiving a third dose of ...
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Attacking cancer tumors with next generation CAR-T cell therapies

Rafael Amado | 
In 2017, the first immuno-oncology cell therapies, known as chimeric antigen receptor T cells, or CAR T, were approved by the ...
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Stem cell treatment could create ‘living drug’ against cancer tumors

Chia-Yi Hou | 
In a first-of-its-kind clinical trial, a natural killer cell immunotherapy derived from induced pluripotent stem cells is being tested for ...
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‘Wildly popular’ and unproven probiotics may interfere with some treatments

Meghana Keshavan | 
Probiotics are wildly popular. After all, the microbial cocktails are available over the counter and have been shown to be ...
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Can CAR-T cell therapy tackle solid tumors too?

Kerry Grens | 
Last summer, [Cecelia] Barron’s cancer went from stage 2 to stage 3 oligodendroglioma. Behnam Badie, her surgeon at City of Hope, ...
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US approves immunotherapy for breast cancer for first time

Sharon Begley | 
Roche’s cancer immunotherapy Tecentriq (atezolizumab), a PD-L1 inhibitor, scored its fifth Food and Drug Administration approval on [March 8], for advanced triple-negative ...
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Combined immunotherapy strategy could revolutionize kidney cancer treatment

Jacqueline Howard | 
The way doctors typically approach kidney cancer treatment could be evolving. Two separate studies published [February 16] in the New ...
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Immunotherapy could extend survival for patients with aggressive glioblastoma brain cancer

Laurie McGinley | 
Glioblastoma — the aggressive brain cancer that killed Sen. John McCain, Sen. Ted Kennedy and Beau Biden, son of Vice President Joe Biden ...
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Boosting the body’s innate cancer immunity

Mark Lowdell | 
The focus on immunotherapy puts us at risk for forgetting that the principal role of the immune system is tumor ...
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Immunotherapy more effective in patients with more cancer mutations, study shows

Catherine Offord | 
The number of mutations in a tumor’s genome may predict how well a patient will benefit from treatment with immune ...
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Targeting cancer with sugar-powered immunotherapy

Esther Landhuis | 
Over the last few decades, researchers tinkering with molecules that turn an immune cell on and off have created a ...
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The future is now: Here are the most promising synthetic biology projects

Dan Fletcher | 
Never has it been more possible to engineer biology (see ‘Tailor, not tinker’). But solving grand problems requires a switch ...
How immunotherapy uses our immune system to attack cancer

How immunotherapy uses our immune system to attack cancer

Charles Graeber | 
Our usual defence against disease is our immune system. It does an excellent job of sorting out what doesn’t belong ...
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Cartoons offer ‘simple’ whimsical look at cancer immunotherapy through the eyes of scientists

Neil Canavan | 
Four years ago, I was hired for a new and terrific job: to help my colleagues at Solebury Trout and ...
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