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Injecting tumors with a flu shot ignites cancer-killing immune response in mice

Nearly 5,000 years ago, Egyptian physician Imhotep observed a grotesque but revealing detail about tumors: some grew so large that ...
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‘A cleaner kill’: Harnessing the body’s immune system to battle cancer

What if your immune system could kill cancers in the same way it does colds and flu? This concept may ...
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Coronavirus immunotherapy could arrive by early summer. Is ‘record time’ fast enough?

Blood-plasma-based cures aren’t just the stuff of movies. There’s plenty of science to back the idea that blood products from ...
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Viewpoint: AI could guide us in understanding which cancer patients likely to benefit from expensive immunotherapy

Over the last decade, significant advances in research, education, early detection methods and treatment have boosted cancer survival rates while ...
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Immunotherapy breakthrough? CRISPR-edited immune cells proven safe for use in cancer patients in early stage trial

Now for the first time in the U.S., researchers say they’ve shown that CRISPR-edited immune cells can be safely given ...
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T-cell that can fight all cancers: Scientists discover promising part of our immune system

Our immune system is our body's natural defence against infection, but it also attacks cancerous cells. The scientists were looking ...
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Refining CAR-T therapy could halt ‘violent, life-threatening’ immune reactions

CAR-T cells that have been so successful against some leukemias and lymphomas often cause a violent and even life-threatening immune ...
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Expensive CAR-T therapy raises difficult question: ‘What is the price of a human life?’

A new type of therapy for certain blood cancers is ingenious but it raises important questions about its cost, both ...
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‘Why didn’t we think of this earlier?’ Immunotherapy could treat more than just cancer

Immunotherapy has transformed cancer care. Now the tools and new knowledge created by this strategy for treating disease by stimulating ...
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Promising immunotherapy drug to treat peanut allergies may be approved although 10% of study subjects had serious side effects

On [September 13], a panel of experts assembled by the Food and Drug Administration voted that the agency should approve a drug ...
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‘It’s very encouraging’: Experimental gene therapy shows promise for glioblastoma patients in clinical trial

An inducible, tumor-localized gene therapy has been tested for the first time in glioblastoma patients. The two-part approach, which involves ...
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Fighting cancer by stimulating the immune system with injections directly into the tumor

This past April, Mount Sinai oncologist Joshua Brody and his team announced a clinical trial that delivers immune modulators directly ...
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‘Cancer vaccine’ boosts survival rates when combined with immunotherapy drugs in small study

The largest study to date of a “cancer vaccine” plus one of the immunotherapy drugs that has revolutionized cancer treatment ...
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Some powerful new cancer drugs trigger diabetes for unknown reasons

The first two rounds of treatment went off without a hitch. But last November, after receiving a third dose of ...
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Attacking cancer tumors with next generation CAR-T cell therapies

In 2017, the first immuno-oncology cell therapies, known as chimeric antigen receptor T cells, or CAR T, were approved by the ...
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Stem cell treatment could create ‘living drug’ against cancer tumors

In a first-of-its-kind clinical trial, a natural killer cell immunotherapy derived from induced pluripotent stem cells is being tested for ...
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‘Wildly popular’ and unproven probiotics may interfere with some treatments

Probiotics are wildly popular. After all, the microbial cocktails are available over the counter and have been shown to be ...
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Can CAR-T cell therapy tackle solid tumors too?

Last summer, [Cecelia] Barron’s cancer went from stage 2 to stage 3 oligodendroglioma. Behnam Badie, her surgeon at City of Hope, ...
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US approves immunotherapy for breast cancer for first time

Roche’s cancer immunotherapy Tecentriq (atezolizumab), a PD-L1 inhibitor, scored its fifth Food and Drug Administration approval on [March 8], for advanced triple-negative ...
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Combined immunotherapy strategy could revolutionize kidney cancer treatment

The way doctors typically approach kidney cancer treatment could be evolving. Two separate studies published [February 16] in the New ...
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Immunotherapy could extend survival for patients with aggressive glioblastoma brain cancer

Glioblastoma — the aggressive brain cancer that killed Sen. John McCain, Sen. Ted Kennedy and Beau Biden, son of Vice President Joe Biden ...
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Boosting the body’s innate cancer immunity

The focus on immunotherapy puts us at risk for forgetting that the principal role of the immune system is tumor ...
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Immunotherapy more effective in patients with more cancer mutations, study shows

The number of mutations in a tumor’s genome may predict how well a patient will benefit from treatment with immune ...
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Targeting cancer with sugar-powered immunotherapy

Over the last few decades, researchers tinkering with molecules that turn an immune cell on and off have created a ...
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The future is now: Here are the most promising synthetic biology projects

Never has it been more possible to engineer biology (see ‘Tailor, not tinker’). But solving grand problems requires a switch ...
How immunotherapy uses our immune system to attack cancer

How immunotherapy uses our immune system to attack cancer

Our usual defence against disease is our immune system. It does an excellent job of sorting out what doesn’t belong ...
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Cartoons offer ‘simple’ whimsical look at cancer immunotherapy through the eyes of scientists

Four years ago, I was hired for a new and terrific job: to help my colleagues at Solebury Trout and ...
Viewpoint: Do male doctors tend to be paternalistic when treating 'female' diseases?

Viewpoint: Do male doctors tend to be paternalistic when treating ‘female’ diseases?

When my silent assassin emerged last autumn, I pressed my surgeon about the prognosis for a form of peritoneal cancer ...