Gene Therapy
Video: How gene therapy could treat rare, incurable ‘day blindness’
[Editor's note. Achromatopsia is a visual disorder sometimes referred to as "day blindness".] Imagine stepping out into a bright South ...
Talking Biotech: Florida neurosurgeon Duane Mitchell on how genetic engineering opens doors in cancer fight
Neuroscientist Duane Mitchell discusses genetically enhancing T-cells and other cutting edge cancer immunotherapies ...
Umbilical cord stem cells may yield treatment for autism
Gracie [Gregory] was one of 25 children who took part in the first-of-its-kind study at Duke University in Durham, North ...
Uncertainty is a certainty in the modern genomics landscape
[Editor's note: Misha Angrist, the new editor-in-chief of Genome, writes about the uncertainties surrounding genomics in modern medicine.] In the last few years ...
Why cells are like computers—And how ‘hacking’ them could lead to new diagnostic tools
Cells are basically tiny computers: They send and receive inputs and output accordingly. If you chug a Frappuccino, your blood sugar ...
On the horizon: Genes pointing to potential Parkinson’s disease therapies
The ongoing revolution in genetics is playing an increasingly important role in our understanding of the [Parkinson's] disease while also revealing ...
Genetically selected people? ‘Polygenic scores’ could soon be used to guide human breeding
Today, for about $100, anyone can receive a million bits of information about their own genetic makeup from a company ...
Unreliable science? Scores of mice studies may be tainted because of standard handling practice
Scores of scientific studies based on mice are being called into question because their behaviour is affected by the way ...
2 young leukemia patients cured with T-cell immunotherapy using genetically engineered donor cells
Gene-edited immune cells cure two British babies with childhood leukemia. But instead of patient-specific cells, doctors used cheaper universal cells ...
No longer waiting idly: Parents of patients establishing gene therapy programs
In recent years, gene therapies have become safer and better at hitting their intended targets in the body, leading to ...
No turning back: Why discussions on gene editing must reach the American public
[F]or the first time, scientists in China announced they had successfully edited the genes of fertilized human embryos, and fully ...
Sickle cell cure? Patient in complete remission following gene therapy
A number of recent headlines imply a recent case study just published...proves that gene therapy has cured sickle cell disease—a ...
Quest for a cure: Gene therapy offers hope for children with rare form of Charcot-Marie-Tooth disease
A couple strives to help their daughter, who was born with a rare form of Charcot-Marie-Tooth, a muscle-wasting disease that ...
Cystic fibrosis, sickle-cell anemia could be corrected in embryos with new CRISPR variant
Since the discovery of the genome-editing tool CRISPR/Cas9, scientists have been looking to utilize the technology to make a significant ...
Return of the woolly mammoth and 3 other ways CRISPR could change the world
The woolly mammoth has been extinct for more than 4000 years. Now scientists are talking about bringing it back with ...
Sickle cell gene therapy offers hope to afflicted families in Africa, where proper care is sparse
[Editor's note: This article is an interview with Sia Evelyn Nyandemo who runs a campaign group to support sickle cell ...
One third of lymphoma patients cancer free after 6 months in CAR-T gene therapy study
An experimental gene therapy that turns a patient's own blood cells into cancer killers worked in a major study, with ...
DIY home gene editing is all the rage: Here are the promises and pitfalls
Kian Sadeghi has postponed homework assignments, sports practice and all the other demands of being a 17-year-old high-school junior...On a ...
Human Genome Project 2: Should scientists synthesize entire human genetic code from scratch?
In May 2016, scientists, lawyers and government representatives converged at Harvard to discuss the Human Genome Project-Write (HGP-Write), a plan ...
Designer dogs? In pursuit of the perfect, healthy canine companion
Centuries of inbreeding have left many dog breeds with a severely limited gene pool, and this lack of genetic diversity ...
For precision medicine to work, physicians must incorporate holistic health factors, like belief
[Editor's note: Dr. Sharon Bergquist is a clinician in the division of general medicine and geriatrics at Emory University. She also ...
‘Superbugs’ could be killed with ‘genetic chainsaw’ version of gene editor CRISPR
When folks talk about the gene-editing tool CRISPR, they’re usually talking about CRISPR-Cas9, a combination of DNA and enzymes that ...
Lung, pancreatic cancers linked to critical gene mutation
Researchers ... have identified a critical gene, FOSL1, in the development of lung and pancreatic cancer. Approximately 25% of patients ...
Weird world of DNA: What’s the best way to help patients with genetic diseases that are not inherited?
The stories of two children, Millie and Hannah, highlight ways that genetic disease can seem to veer from the predictions ...
Autism, other brain disorders linked to network of 91 genes
Gene discovery research is uncovering similarities and differences underlying a variety of disorders affecting the developing brain, including autism, attention ...
On/off switch? Chronic pain could be eased if we identify the right genes
[Editor's note: Blair Smith is a professor of population science at the University of Dundee in Scotland.] Two of the ...
Who should own revolutionary gene editor CRISPR? Scientists or the public?
In a one sentence ruling, an appeals board granted the rights to the powerful gene editing technology CRISPR-Cas9 to the ...